RLF publications

Institute of Adaptive & Spaceflight Physiology
Graz, Austria
Institut für Adaptive und Raumfahrtphysiologie

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Scientific publications: Austromir and RLF

10 Years Space Biomedical Research and Development in Austria
Facultas Verlag Austria, Vienna -- ISBN 3-85076-572-5

Contents:

A. Grigoriev, IBMP: A successful bilateral cooperation

R. White, NSBRI: Space biomedical research in Austria

D. Schmitt, ESA: The future of life science research in the context of space exploration

W. Pseiner, ASA: The Austrian Space Agency's perspective

H. Hinghofer-Szalkay, ASM: It's the future that counts

Chapters:

M. Berger, S. Lechner-Steinleitner, I. Kozlovskaya, M. Marosi, S. Mescheriakov, S. Golaszewsky, F. Gerstenbrand: Neurological aspects in real and simulated spaceflight
E. Gallasch, D. Rafolt, I. Kozlovskaya: Space flight induced changes of muscle tone and limb tremor and new directions in neuromechanography
H. Hinghofer-Szalkay, J.E. Greenleaf, V. Noskov: Human body fluid volume regulation in real and simulated spaceflight
G. Koehler, D. Ruenzler, B. Mayer, M. Sara, S. Rasmussen, L. Buravkova: Molecular self-assembly and self-organization in microgravity. Applications to biotechnology and bioorganic materials science
W. Mayr, D. Rafolt, M. Bijak, W. Girsch, C. Hofer, H. Lanmueller, M. Reichel, S. Sauermann, C. Schmutterer, E. Unger, V. Gratchev, Y. Koryak, B. Shenkman, I. Kozlovskaya, A. Grigoriev, G. Freilinger: Functional Electrical Stimulation (FES) as a countermeasure against muscular atrophy in long-term space flights -- first application on board the MIR-Station
H. Tschan, N. Bachl, R. Baron, V. Polyakov, I. Kozlovskaya: Resistance training - a strategy proposed to counteract physical deconditioning in microgravity
H. Tuschl, E. Weber, M. Rykova, I. Konstantinova: Immunological investigations in long duration cosmonauts
N. Vana, M. Noll, W. Schoener, M. Fugger, F.Y. Akatov, V. Shurshakov, T. Berger, M. Hajek: Measurements of the biological relevant dose in space, aircraft and during medical applications using the newly developed HTR-method

Original Publications

(alphabetical order: first author's name)

Bachl N, Tschan H, Baron R, Koszlovskaya I, Mossaheb M, Bumba W, Albrecht R. Motomir experiment - muscle strength under conditions of weightlessness. Space Technol. 1996; 16: 215-30.
Bachl N, Baron R, Tschan H, Mossaheb M, Bumba W, Hildebrand F, Knauf M, Witt M, Albrecht R, Kozlovskaya I, Charitonov N: Grundlagen der muskulaeren Leistungsfaehigkeit under Bedingungen der Schwerelosigkeit (Principles of muscular efficiency under conditions of weightlessness). Wien med Wschr. 1993; 143: 588-610.
Benke Th, Koserenko O, Watson NV, Gerstenbrand F. Space and cognition: The measurement of behavioral functions during a 6-day space mission. Aviat Space Environ Med. 1993; 64: 376-9.
Benke Th. Die klinische und experimentelle Anwendung von Cogimir (The clinical and experimental application of Cogimir). Wien med Wschr. 1993; 143: 610-3.
Berger M, Lechner-Steinleitner S, Kozlovskaya I, Holzmüller G, Mescheriakov S, Sokolov A, Gerstenbrand F. The effect of head-to-trunk position on the direction of arm movements before, during, and after space flight. J Vestib Res. 1998; 8: 1-15.
Berger M, Mescheriakov S, Molokanova E, Lechner-Steinleitner S, Seguer N, Kozlovskaya I. Pointing arm movements in short- and long-term spaceflights. Aviat Space Environ Med. 1997; 68: 781-7.
Berger M, Gerstenbrand F, DeCol Ch, Grill L, Muigg A, Kozlovskaya I, Burlatchkova M, Sokolov A, Babaev B, Borisov M, Mossaheb M, Steinwender G, Hochmair E: Bewegungsstoerungen in der Schwerelosigkeit (Movement disorders in weightlessness). Wien med Wschr. 1993; 143: 614-9.
Berger M, Hochmair E, Holzmüller G, Ostermann M, Steinwender G. Bewegungsanalyse unter Mikrogravitation: Theorie und Praxis zur Berechnung der Zielbewegung mit der MONIMIR-Helmlampe. Biomed Technik 1992; 37: 73-7.
Gallasch E, Kenner T. Microvibration as a function of muscle tone studied in microgravity. Naturwiss. 1998; 85: 28-30.
Gallasch E, Kenner T. Characterisation of arm microvibration recorded on an accelerometer. Eur J Appl Physiol. 1997; 75: 226-32.
Gallasch E, Moser M, Kozlovskaya IB, Kenner T, Noordergraaf A. Effects of an eight-day space flight on microvibration and physiological tremor. Am J Physiol. 1997; 273: R86-92.
Gallasch E, Rafolt D, Moser M, Hindinger J, Eder H, Wiesspeiner G, Kenner T. Instrumentation for assessment of tremor, skin vibrations, and cardiovascular variables in MIR-space missions. IEEE Transact Biomed Eng. 1996; 43: 328-33.
Gallasch E, Kozlovskaya I, Löscher WN, Konev A, Kenner T. Arm tremor and precision of hand force control in a short and long term flight on the MIR space station. Acta Astronautica 1994; 33: 49-55.
Gallasch E, Loescher WN, Moser M, Kenner T, Kozlovskaya I, Konev A. Mikrovib - eine Testbatterie fuer Untersuchungen zum physiologischen Tremor (Mikrovib - a test battery for the investigation of physiological tremors). Wien med Wschr. 1993; 143: 620-5.
Hinghofer-Szalkay HG, Noskov VB, Roessler A, Grigoriev AI, Kvetnansky R, Polyakow VV. Endocrine status and LBNP-induced hormone changes during a 438-day space flight. Aviat Space Environ Med. 1999; 70: 1-5.
Hinghofer-Szalkay HG, Noskov VB, Schmied J, Roehrer R, Viehboeck F, Koenig EM, Sauseng-Fellegger G, Zambo-Polz C, Heimel H, Grigoriev AI. Changes in blood and plasma composition with lower body negative pressure on the ground and in space in one subject. Aviat Space Environ Med. 1994; 65: 214-9.
Hinghofer-Szalkay HG, Noskov V, Jezova D, Sauseng-Fellegger G, Füger GF, Sukhanov Y, König EM, Zambo-Polz C, Barowitsch C, Viehboeck F, Macho L, Kvetnansky R, Grigoriev AI. Hormonal changes with lower body negative pressure on the 6th day in microgravity in one cosmonaut. Aviat Space Environ Med. 1993; 64: 1000-5.
Hinghofer-Szalkay H, Noskov VB. Das interstitielle Organ im schwerelosen Zustand - ein klinisch-physiologisches Modell? (The interstitial organ in microgravity: a model for clinical physiology?) Wien med Wschr. 1993; 143: 626-9.
Moser M, Lehofer M, Hildebrandt G, Voica M, Egner S, Kenner T. Phase - and frequency coordination of cardiac and respiratory function. Biol Rhythm Res. 1995; 26: 100-11.
Müller Ch, Wiest G, Kornilova L, Deecke L. Visuo-vestibulaere Interaktion zur Bestimmung des Orientierungsverhaltens in der Schwerelosigkeit (Visuo-vestibular interaction and spatial orientation in microgravity). Wien med Wschr. 1993; 143: 630-2.
Müller Ch, Schnider P, Persterer A, Opitz M, Nefjodova MV, Berger M. Angewandte Psychoakustik im Weltraum (Applied psychoacoustics in microgravity). Wien med Wschr. 1993; 143: 633-5.
Noll M, Vana N, Schoener W, Fugger M. Measurements of the equivalent dose in aircraft with TLDs. Radiat Protect Dosimetry 1999; 85: 283-6.
Noll M, Boeck E, Schoener W, Egger P, Wolf C, Ruediger H, Vana N. Correlation of the LET-dependent TL-response of LIF:Mg,Ti TL-dosemeters and gentoxic endpoints after proton irradiation. Appl Radiat Isotopes 2000; 52: 1135-8.
Noskov VB, Sukhanov YV, Volkov AA, Hinghofer-Szalkay H, König E, Sauseng-Fellegger G, Viehböck F, Kvetnansky R, Jezova D, Macho L. Assessment of the reactivity of cosmonaut´s hormonal regulation system during LBNP test during Soviet-Austrian flight onboard orbital station "MIR". Aerosp Environ Med. 1994; 28: 33-7
Rafolt D, Gallasch E. Body fixed ankle dynamometer for isometric tests in space flights. Biomed Technik 1996; 41: 91-7.
Rössler A, Laszlo Z, Haditsch B, Hinghofer-Szalkay H. Orthostatic stimuli rapidly change plasma adrenomedullin in humans. Hypertension 1999; 34: 1147-51.
Roessler A, Noskov V, Laszlo Z, Polyakov VV, Hinghofer-Szalkay H. Permanent depression of plasma cGMP during long-term space flight. Physiol Res. 2001; 50:
Schöner W, Vana N, Fugger M. The LET dependence of LiF:Mg,Ti dosimeters and its application for LET measurements in mixed radiation fields. Radiat Protect Dosimetry 1999; 85: 263-6.
Tuschl H, Kovac R, Klein W, Voronkov YI, Chaidakow M. Influence of microgravity on immune system and genetic information. Space Technol. 1993; 2: 199-203.
Tuschl H, Kovac R, Klein W, Ott E, Voronkov YI, Kaidakow M. Genetische und immunologische Untersuchungen nach einem Raumflug (Genetic and immunological investigations after a spaceflight). Wien med Wschr. 1993; 143: 636-8.
Vana N, Schoener W, Fugger M, Akatov Y. Absorbed dose measurement and LET determination with TLDs in space. Rad Prot Dosimetry 1996; 66: 145-52.
Vana N, Schöner W, Fugger M, Akatov Y, Shurshakov V. ADLET - absorbed dose and average LET determination with TLDs on the space station MIR during a Russian long-term flight. Rad Prot Dosimetry 1996; 66: 173-7.
Vana N, Schöner W, Noll M, Fugger M, Akatov Y, Shurshakov V. Determination of the absorbed dose and the average LET of space radiation in dependence of shielding conditions. Radiat Protect Dosimetry 1999; 85: 291-4.

Book Chapters

Bachl N, Baron R, Tschan H, Mossaheb M, Stockhammer H, Bumba W, Kozlovskaya I, Kharitonov K, Albrecht R, Hildebrandt F, Witt M, Knauf M. Development and implementation of the MOTOMIR ex-periment on the MIR space station. In: Austrian Society for Aerospace Medicine (ed.): Health from Space Research: Austrian Accomplishments. Wien: Springer Verlag 1992 (ISBN 3-211-82413-8), pp. 137-54.
Benke Th, Kosorenko O, Gerstenbrand F. COGIMIR - how to measure cognitive functions in space. In: Health from Space Research. Wien: Springer Verlag 1992, pp. 55-63.
Berger M, Gerstenbrand F, Kozlovskaya IB, Burlatchkova N, Muigg A, Sokolov A, Babaev B, Grill I, Borisov M, DeCol C, Holzmueller G, Hochmair E, Steinwender G. Eye, head and arm coordination and spinal reflexes in weightlessness - MONIMIR experiment. In: Health from Space Research. Wien: Springer Verlag 1992, pp. 119-35.
Berger M, Mescheriakov S, Molokanova E, Lechner S, Gerstenbrand F, Kozlosvkaya I, Babaev B, Sokolov A. Influence of short- and long-term exposure to real microgravity on kinematics of pointing arm movements. In: T Mergner, F Hlavacka (eds). Multisensory Control of Posture. New York: Plenum Press 1995, pp. 339-45.
Feichtinger Ch, Jossek B, Berzhatyi V, Batenchuk-Tusko T, Kozharinov V. Acceptance-, qualification- and delivery procedures for AUSTROMIR 91 hardware. In: Health from Space Research. Wien: Springer Verlag 1992, pp. 1-10.
Gallasch E, Moser M, Kenner T, Kozlovskaya I, Konev A, Borisov M. Experiment MICROVIB - investigation of tremors in microgravity. In: Health from Space Research. Wien: Springer Verlag, pp. 85-107.
Harich H, Friedmann M, Kroenle I. Countdown for AUSTROMIR. In: Health from Space Research. Wien: Springer Verlag 1992, pp. 11-19.
Hinghofer-Szalkay HG, König EM, Noskov NB, Sauseng-Fellegger G. BODYFLUIDS. In: Health from Space Research. Wien: Springer Verlag 1992, pp. 39-53.
Hinghofer-Szalkay H. Schwerkraft und Blutvolumen: Regulatorische Aspekte. In: H. Hinghofer-Szalkay (ed.): Physiologie an der Schwelle zum 21. Jahrhundert. Blackwell Wissenschafts-Verlag, Berlin / Wien 2000. ISBN 3-89412-428-8.
Moser M, Gallasch E, Rafolt D, Jernej G, Kemp C, Moser-Kneffel E, Kenner T, Baevskij R, Funtova L. Cardiovascular monitoring in microgravity - the experiments PULSTRANS and SLEEP. In: Health from Space Research. Wien: Springer Verlag, pp. 167-89.
Mueller Ch, Kornilova L, Wiest G, Deecke L. OPTOVERT - Vertical optokinetic stimulation used to examine central orientation processes. In: Health from Space Research. Wien: Springer Verlag 1992, pp. 155-65.
Persterer A, Berger M, Koppensteiner C, Mueller C, Nefjodova M, Opitz M. AUDIMIR-Directional hearing at microgravity. In: Health from Space Research. Wien: Springer Verlag 1992, pp. 21-38.
Tuschl H, Klein W, Kovac R, Ott E, Chajdakow MS, Voronkov YJ. Experiment MIRGEN. In: Health from Space Research. Wien: Springer Verlag 1992, pp. 109-18.
Vana N, Schöner W, Fugger M, Akatov Y. DOSIMIR - radiation measurements inside the Soviet space station MIR. In: Health from Space Research. Wien: Springer Verlag 1992, pp. 65-83.

Proceedings

Bachl N, Baron R, Tschan H, Kozlovskaya I, Charitonov N, Mossaheb M, Bumba W, Albrecht R, Hildebrand F. Results of strength behaviour of arm and leg muscles during short and extended space flight on MIR space station. 10th IAA Man in Space Symposium, Tokyo, April 19-23, 1-6, 1993.
Bachl N, Baron R, Tschan H, Petschnig R, Laube W. Charakterisierung des funktionellen Muskelstatus mittels EMG und translatorischer Ergometrie in Schwerelosigkeit. Dtsch Zschr Sportmed S 30-3, 1994.
Berger M, Gerstenbrand F, Burlatschkova N, Muigg A, Grill L, Holzmueller G, Kozlovskaya IB, Borisov M, Babaev B, Sokolov A, Hochmair E, Steinwender G. Eye-head-arm coordination and spinal reflexes in weightlessness. International Space Year Conference, Munich, March 30 - April 4, pp. ?, 1992 .
Gallasch E, Burlatschkowa N, Beljajeva I, Moser M, Kenner T. Is physiological tremor (microvibration) influenced by microgravity? Fourth European Symposium on Life Sciences, Trieste, May 28 - June 1, 107-10, 1990.
Gallasch E, Kozlovskaya IB, Moser M, Borisov M, Hindinger J, Konev A, Kenner T. The effect of micro-gravity on tremor (microvibration). Satellite Symposium: Columbus Eight (COSY-8) Utilization of Earth orbiting Laboratories, International Space Year Conference, Munich, March 30- April 4, 175-80, 1992.
Gallasch E, Rafolt D, Kenner T. Modeling of 8-12 Hz mechanical oscillations in relaxed arm segments. IEEE Proc. 964-5, 1993.
Gallasch E, Kozlovskaya IB, Konev A, Rafolt D, Loescher W, Moser M, Hindinger J, Eder H, Kenner T. Results of one short and two long term flights on human physiological tremor and microvibration. 5th European Symp. on Life Science Research in Space, Arcachon, Sept. 26 - Oct. 1 1993, 361-6 (1994)
Haditsch B, Noskov VB, Roessler A, Polyakov VV, Hinghofer-Szalkay HG. Confinement of real and simulated spaceflight seems to depress plasma ANP and cGMP. The 11th International Hypoxia Symposium, Jasper, Alberta, Canada 1999, p. 160.
Hindinger J, Gallasch E, Wieflpeiner G. Digitalelektronik und Experimentsoftware fuer das MIR-Projekt. Biomed Technik. 1993; 38 (Ergaenzungsband) 109-10.
Hinghofer-Szalkay HG. Achievements in medical research in space. ESA Symposium on Space Station Utilization, Darmstadt, Sept. 30-Oct. 2, 67-73, 1996.
Hinghofer-Szalkay H. Do hormones stabilize brain function during space flight? Congress on cerebral ischemia, vascular dementia, epilepsy and CNS injury - New aspects of prevention and treatment from space and underwater exploration, May 9-13, 1998, Washington, DC
Rafolt D, Gallasch E, Anzberger K, Guter M, Kenner T, Mayr W, Messerschmidt D, Moser M, Schaupp L, Schnetz G, Zeiringer H. Entwicklung von Sensortechnologien fuer medizinische Experimente waehrend Langzeitfluegen auf der Raumstation MIR. Biomed Technik. 1995, 40 (Ergaenzungsband) 105-7.
Rafolt D, Gallasch E, Mayr W. A spaceapproved ankle dynamometer for isometric tests. 9th Intl Conf on Mechanics in Medicine and Biology, Ljubljana, June 30 - July 4, 215-7, 1996.
Rössler A, Hinghofer-Szalkay H, Noskov V, Laszlo Z, Polyakov VV. Diminished plasma cGMP during weightlessness. J Gravitat Phys 1997; 4: P101-2.
Schöner W, Vana, N, Fugger M, Pohn E, Akatov Y. Messungen des mittleren LET der Strahlung im Weltraum mit TLDs und die mikrodosimetrische Interpretation von LET-abhaengigen Effekten. IRPA Symposium, Hannover, Oct. 23-25, 130-4, 1996.
Tschan H, Bachl N, Baron R, Kozlovskaya IB, Charitonov N, Mossaheb M, Bumba W, Albrecht R, Hildebrandt F. Specific strength diagnostics in long term spaceflight. 5th European Symp. on Life Sciences Research in Space, Arcachon, Sept. 26 - Oct. 1, 401-4, 1994.
Tuschl H, Kovac R, Klein W, Ott E, Voronkov YI, Kaidakow M. Influence of microgravity on immune system and genetic information. International Space Year Conference, Munich, March 30 - April 4, 187-91, 1992.
Vana N, Schöner W, Fugger M, Akatov Y. A new experimental approach in depth dose LET-determination on satellites photon-8 and bion-10. IAF/IAA-94-G.2.139, 1-5, 1994.
Vana N, Schöner W, Fugger M, Akatov Y, Shurshakov V. Measurement of absorbed dose and average LET in the space station MIR and on space shuttles. IRPA Intl Congress on Radiation Protection, Vienna, April 14-19, 2-253-5, 1996.
Vana N, Schöner W, Noll M, Fugger M, Akatov Y, Shurshakov V. HTR - A method for dose determination and assessment of the effectiveness of space radiation. XIth Conference on Space Biology and Aerospace Medicine 2: 386-8, Moscow 1998.