Myeloid Cells & Leukemia

The "Myeloid Cells & Leukemia"; group aims to identify novel pathogenetic mechanisms in acute myeloid leukemia (AML). This aggressive disorder develops throughout life but is commonly encountered above the age of 60 years. Unfortunately, despite intensive treatment strategies the prognosis of patients with AML is dismal.

The aim of our research is to understand mechanisms of myeloid leukemogenesis, identify critical molecular aberrations as targets for novel leukemia therapies and translate these data into patient benefit. Our location within a tertiary care cancer center has enabled us to establish a large collection of primary leukemia specimens. Furthermore, access to outstanding research facilities within the Medical University of Graz allows us to employ state-of-the-art leukemic cell culture and mouse models. The research group comprises independent investigators who share their expertise with biologists, medical scientists, students and technicians.